41,756 research outputs found

    Three-loop HTLpt thermodynamics at finite temperature and chemical potential

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    In this proceedings we present a state-of-the-art method of calculating thermodynamic potential at finite temperature and finite chemical potential, using Hard Thermal Loop perturbation theory (HTLpt) up to next-to-next-leading-order (NNLO). The resulting thermodynamic potential enables us to evaluate different thermodynamic quantities including pressure and various quark number susceptibilities (QNS). Comparison between our analytic results for those thermodynamic quantities with the available lattice data shows a good agreement.Comment: 5 pages, 6 figures, conference proceedings of XXI DAE-BRNS HEP Symposium, IIT Guwahati, December 2014; to appear in 'Springer Proceedings in Physics Series

    Emerging treatment options for the management of brain metastases in patients with HER2-positive metastatic breast cancer.

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    The widespread use of trastuzumab in the past decade has led to a significant and measureable improvement in the survival of patients with human epidermal growth factor receptor-2 (HER2) overexpressing breast cancer, and in many ways has redefined the natural history of this aggressive breast cancer subtype. Historically, survival in patients with HER2-positive disease was dictated by the systemic disease course, and what appears to be the central nervous system (CNS) tropism associated with HER2-amplified tumors was not clinically evident. With improved systemic control and prolonged survival, the incidence of brain metastases has increased, and CNS disease, often in the setting of well-controlled extracranial disease, is proving to be an increasingly important and clinically challenging cause of morbidity and mortality in patients with HER2-positive advanced breast cancer. This review summarizes the known clinical data for the systemic treatment of HER2-positive CNS metastases and includes information about ongoing clinical trials of novel therapies as well as emerging strategies for early detection and prevention

    The fifth most prevalent disease is being neglected by public health organisations

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    The progress towards reduction of global mortality has produced an epidemiological transition towards non-fatal diseases, which challenge the ability of the world’s population to live in full health. Although traumatic dental injuries are not lethal, their treatment is more expensive (US$2 000 000–5 000 000 per million inhabitants) and time-consuming than that of all the other bodily injuries, making dental rehabilitation less likely among disadvantaged individuals. Since untreated traumatic dental injuries have a negative social, functional, and emotional effect in children and adolescents, differences in treatment of these injuries between children from different countries and social classes produce disparities in their quality of life

    RECREATIONAL SWIMMING BENEFITS OF NEW HAMPSHIRE LAKE WATER QUALITY POLICIES: AN APPLICATION OF A REPEATED DISCRETE CHOICE MODEL

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    Water pollution control policies generally direct sources (i.e., industry, agriculture) to reduce loadings of certain pollutants. Thus, evaluating the relative net recreation benefits of policies to improve water quality requires establishing a linkage between the sources, the resultant water quality degradation at the affected water bodies, and, ultimately, the effect on recreation behavior. This linkage is rarely present in the empirical literature which is, thus, deficient for water pollution control policy assessment purposes. In this paper, we estimate the relative recreational swimming benefits that may result from controlling point and nonpoint sources of pollution, respectively, in New Hampshire's lakes. We use a repeated discrete choice framework to model swimming behavior as a function of each lake's level of eutrophication, bacteria, and oil and grease. For each pollutant, at each affected lake, we identify which source is responsible for the pollution, and we conduct scenarios controlling each pollution source independently, and then, taken together. Seasonal benefit estimates are presented for each scenario. Coupled with information on the most cost effective means of generating the scenarios, these estimates provide a useful starting point for a quantitative assessment of the net recreation benefits of policies to improve the quality of New Hampshire lakes.Environmental Economics and Policy,

    Developing modern multifunctional agroforestry systems for sustainable intensification

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    Agroforestry is a land-use system that integrates trees and shrubs with crops and/or livestock production. It has been identified by the International Assessment of Agricultural Knowledge, Science and Technology for Development (IAASTD, 2008) as a ‘win-win’ approach that balances the production of commodities (food, feed, fuel, fibre, etc.) with non-commodity outputs such as environmental protection and cultural and landscape amenities. This paper will review the potential of agroforestry as part of a multifunctional working landscape in temperate regions, and will consider management and policy implications of widespread adoption of this form of land-use

    Observation of Conduction Band Satellite of Ni Metal by 3p-3d Resonant Inverse Photoemission Study

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    Resonant inverse photoemission spectra of Ni metal have been obtained across the Ni 3pp absorption edge. The intensity of Ni 3dd band just above Fermi edge shows asymmetric Fano-like resonance. Satellite structures are found at about 2.5 and 4.2 eV above Fermi edge, which show resonant enhancement at the absorption edge. The satellite structures are due to a many-body configuration interaction and confirms the existence of 3d8d^8 configuration in the ground state of Ni metal.Comment: 4 pages, 3 figures, submitted to Physical Review Letter
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